Homer is Marge's husband. Marge knows that Homer likes to eat pork chops, and often cooks them him for dinner.
Bart is Marge's eldest child. She does not see him very often, as shown in Snospis Eht: Sick Bart part 2: A trip to the Seaside., when Marge said that she has not been in his room for over eighteen days.
Marge spends a lot of time with Lisa in the basement, playing video games and drinking alcohol.
Not much is known about Marge's relationship with real Maggie. She is unaware that the real Maggie is dead and her place has been taken.
Marge is unaware that fake Maggie is an adult male who has taken real Maggie's place. Marge likes Maggie, but it is unrequited as Maggie is often seen behaving violently towards Marge, such as ripping a Christmas wreath off the wall in Snospis Eht: Christmas Special: Part 03, and hitting her over the head with a teapot in Snospis Eht: Marges Day: Part 01.
Marge gets along well with her mother, but in Snospis Eht: Dreams Again., Marge's mother gets annoyed at the fact that Marge did not invite her to Christmas dinner. Marge's excuse was they thought she was dead.
Marge does not see Ned very often, but in marge simpsons blog 01, Marge recalls how Ned told her to wear shoes when she goes to the woods.
Marge spent most of her childhood with Mister Hitler and they are best friends.
Marge was once robbed by Eskimos on her way back from the Kwik-E-Mart.
Marge belives very strongly in the Snospis family's Christmas traditions, and is therefore overjoyed when Mantra Claws turned up at the Snospis family's Christmas dinner in Snospis Eht: Christmas Special: Part 03.
Marge dislikes horses, describing them as "evil beasts", due to an incident where she was injured by a horse when trying to attack one.
Marge has a fear of wolves due to having to avoid them during her childhood; her mother telling her to come inside before the wolves get her. As a result, Marge once had a nightmare where wolves broke into the house.